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Common Conditions:


PPh3 + H2O

The reaction of azides with triphenylphosphine (PPh3) is typically very fast and high yielding. The resulting iminophosphoranes are hydrolyzed in the presence of H2O to give amines.[1]






Reaction Map:


The reaction map is intended to provide insight into possible reactions one step before and after the title reaction. It also serves as an alternative way to navigate the website, and as a means of coming up with retrosynthetic ideas. Click on the reaction arrow to visit the page.


     
     
 
     
     
     



References:


1) Kurti, L.; Czako, B.; Strategic Applications of Named Reactions in Organic Synthesis