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2. Alc to Halide
3. Alc to Cl
4. Ex [SOCl2 (neat)]

Alcohol to Chloride

[SOCl₂ (neat)]

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Examples:

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Example 1

The SM (1.9 g, 12.5 mmol) was dissolved in SOCl2 (3 mL, 41.1 mmol) and refluxed for 1 h. The mixture was concentrated in vacuo to provide the product as a yellow oil that was used without further purification. [1.9 g, 91%]

[Patent Reference: WO2005082859, page 145, (25.9 MB)]