UHP

(Urea Hydrogen Peroxide)

Other Names:

Urea peroxide

Percarbamide

Carbamide peroxide

General Information:

Structure:

CAS Number: 124-43-6

Molecular Weight: 94.07 g/mol

Appearance: White solid

Melting Point: 90-93 C

Urea hydrogen peroxide (UHP) is a white crystalline solid that consists of 1:1 urea/hydrogen peroxide. As a solid, UHP serves as an easy to handle alternative to aqueous hydrogen peroxide. UHP dissolves in water to provide free hydrogen peroxide.

Common Uses:

Reagent for the conversion of nitriles to primary amides

Procedure excerpt:

To a stirred solution of urea hydrogen peroxide (4.2 g, 43.8 mmol) in H2O (12 mL) was added NaOH (1.04 g, 25.5 mmol). The resulting mixture was cooled in an ice bath . . .

[full procedure]

Safety:

Urea hydrogen peroxide serves as an anhydrous source of hydrogen peroxide. Hydrogen peroxide is a strong oxidizing agent. Hydrogen peroxide is well known to have the potential to cause explosive reactions. Handle with care.

References:

1) Patent Reference: WO2012069948, page 63, (3.9 MB)

2) Wikipedia: Hydrogen peroxide - urea (link)

3) www.sigmaaldrich.com: Urea hydrogen peroxide (link)

4) Burke, S. D.; Danheiser, R. L.; Handbook of Reagents for Organic Synthesis, Oxidizing and Reducing Agents