PyBOP

Other Names:

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium

hexafluorophosphate

General Information:

Structure:

CAS Number: 128625-52-5

Molecular Weight: 520.40 g/mol

Appearance: White solid

Common Uses:

Reagent for amide couplings

Procedure excerpt:

A mixture of the acid (200 mg, 0.81 mmol), the amine (120 mg, 1.0 mmol), and TEA (0.29 mL, 1.6 mmol) in DMF (4 mL) was treated with PyBOP (380 mg, 1.0 mmol). . . .

[full procedure]

References:

1) Patent Reference: WO2015105749, page 89, (11.4 MB)

2) Wikipedia: PyBOP (link)

3) www.sigmaaldrich.com: PyBOP (link)