Cyclohexane

General Information:

Structure:

CAS Number: 110-82-7

Molecular Weight: 84.16 g/mol

Appearance: Colorless liquid

Melting Point: 6.5 C

Boiling Point: 81 C

Cyclohexane is a colorless liquid with a detergent-like odor. It is used occasionally in organic chemistry as a solvent/co-solvent for purposes such as silica gel purifications or compound recrystallizations.

Common Uses:

Solvent/co-solvent (mobile phase) for silica gel chromatography

Procedure Excerpt:

. . . The resulting material was purified by silica gel column chromatography (30-50% EtOAc/cyclohexane) to provide the product . . .

[full procedure]

Safety:

Cyclohexane is a flammable liquid.

References:

1) Patent Reference: WO2015177325, page 71, (4.3 MB)

2) Wikipedia: Cyclohexane (link)

3) www.sigmaaldrich.com: Cyclohexane (link)